Lack of Drug Dosing Guidelines for Critically Ill Patients Receiving Continuous Renal Replacement Therapy
Identifieur interne : 004874 ( Main/Exploration ); précédent : 004873; suivant : 004875Lack of Drug Dosing Guidelines for Critically Ill Patients Receiving Continuous Renal Replacement Therapy
Auteurs : S L Goldstein [États-Unis] ; T D Nolin [États-Unis]Source :
- Clinical Pharmacology & Therapeutics [ 0009-9236 ] ; 2014-08.
Descripteurs français
- KwdFr :
- Antibactériens (administration et posologie), Atteinte rénale aigüe (traitement médicamenteux), Atteinte rénale aigüe (épidémiologie), Food and Drug Administration (USA) (normes), Guides de bonnes pratiques cliniques comme sujet (normes), Humains, Maladie grave (), Maladie grave (épidémiologie), Relation dose-effet des médicaments, Sociétés médicales (normes), Traitement substitutif de l'insuffisance rénale (normes), États-Unis d'Amérique (épidémiologie).
- MESH :
- administration et posologie : Antibactériens.
- normes : Food and Drug Administration (USA), Guides de bonnes pratiques cliniques comme sujet, Sociétés médicales, Traitement substitutif de l'insuffisance rénale.
- traitement médicamenteux : Atteinte rénale aigüe.
- épidémiologie : Atteinte rénale aigüe, Maladie grave, États-Unis d'Amérique.
- Humains, Maladie grave, Relation dose-effet des médicaments.
- Pascal (Inist)
- Wicri :
- geographic : États-Unis.
- topic : Homme, Médicament, Recommandation.
English descriptors
- KwdEn :
- Acute Kidney Injury (drug therapy), Acute Kidney Injury (epidemiology), Anti-Bacterial Agents (administration & dosage), Continuous process, Critical Illness (epidemiology), Critical Illness (therapy), Dose-Response Relationship, Drug, Drug, Human, Humans, Kidney, Patient, Posology, Practice Guidelines as Topic (standards), Recommendation, Renal Replacement Therapy (standards), Replacement therapy, Societies, Medical (standards), United States (epidemiology), United States Food and Drug Administration (standards).
- MESH :
- chemical , administration & dosage : Anti-Bacterial Agents.
- geographic , epidemiology : United States.
- drug therapy : Acute Kidney Injury.
- epidemiology : Acute Kidney Injury, Critical Illness.
- standards : Practice Guidelines as Topic, Renal Replacement Therapy, Societies, Medical, United States Food and Drug Administration.
- therapy : Critical Illness.
- Dose-Response Relationship, Drug, Humans.
Abstract
Acute kidney injury requiring continuous renal replacement therapy is common, costly, and associated with mortality rates of up to 60%. Accurate pharmacokinetic data are essential to developing rational individualized dosing strategies and providing optimal care to these patients, yet few such data exist, probably due in part to an absence of regulatory guidance on the issue. The Kidney Health Initiative is working with stakeholders to propose strategies to address this in a standardized manner.
Url:
- https://api.istex.fr/document/F299E003B570D16CA509A8C1B3A3DA3E4EF682A6/fulltext/pdf
- https://api.istex.fr/document/F299E003B570D16CA509A8C1B3A3DA3E4EF682A6/fulltext/pdf
DOI: 10.1038/clpt.2014.102
Affiliations:
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Le document en format XML
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Nolin</name><affiliation wicri:level="3"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pennsylvania, Pittsburgh</wicri:regionArea><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Clinical Pharmacology & Therapeutics</title><title level="j" type="alt">CLINICAL PHARMACOLOGY & THERAPEUTICS</title><idno type="ISSN">0009-9236</idno><idno type="eISSN">1532-6535</idno><imprint><biblScope unit="vol">96</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="159">159</biblScope><biblScope unit="page" to="161">161</biblScope><biblScope unit="page-count">3</biblScope><date type="published" 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xml:lang="fr"><term>Antibactériens</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Acute Kidney Injury</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Acute Kidney Injury</term><term>Critical Illness</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Food and Drug Administration (USA)</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Sociétés médicales</term><term>Traitement substitutif de l'insuffisance rénale</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Practice Guidelines as Topic</term><term>Renal Replacement Therapy</term><term>Societies, Medical</term><term>United States Food and Drug Administration</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Critical Illness</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Atteinte rénale aigüe</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Atteinte rénale aigüe</term><term>Maladie grave</term><term>États-Unis d'Amérique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Dose-Response Relationship, Drug</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Maladie grave</term><term>Relation dose-effet des médicaments</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>En continu</term><term>Homme</term><term>Malade</term><term>Médicament</term><term>Posologie</term><term>Recommandation</term><term>Rein</term><term>Traitement substitutif</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>États-Unis</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term><term>Médicament</term><term>Recommandation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Acute kidney injury requiring continuous renal replacement therapy is common, costly, and associated with mortality rates of up to 60%. Accurate pharmacokinetic data are essential to developing rational individualized dosing strategies and providing optimal care to these patients, yet few such data exist, probably due in part to an absence of regulatory guidance on the issue. The Kidney Health Initiative is working with stakeholders to propose strategies to address this in a standardized manner.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region><settlement><li>Pittsburgh</li></settlement></list><tree><country name="États-Unis"><noRegion><name sortKey="Goldstein, S L" sort="Goldstein, S L" uniqKey="Goldstein S" first="S L" last="Goldstein">S L Goldstein</name></noRegion><name sortKey="Nolin, T D" sort="Nolin, T D" uniqKey="Nolin T" first="T D" last="Nolin">T D Nolin</name><name sortKey="Nolin, T D" sort="Nolin, T D" uniqKey="Nolin T" first="T D" last="Nolin">T D Nolin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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